Before exploring this month’s issue of Annals, I want to bring to your attention a new benefit that Annals and ACAAI offer to NIH-sponsored researchers. As you may be aware, the agency now requires that all NIH-funded research be published in open access. Annals (with financial support from ACAAI) will support open-access publication at no cost when the research is NIH-sponsored and no other publication funding is available. For details and more information, read the editorial from Dr. Mitch Grayson, Annals Editor-in-Chief.
As spring turns to summer, the current issue of Annals of Allergy, Asthma & Immunology focuses on food allergy and asthma, highlighting outcomes we should consider when treating our patients. Jodi Shroba and colleagues discuss how natural disasters uniquely affect people with food allergies and increase risk as global warming disrupts the food supply. Drs. Arjola K. Cosper and J. Andrew Bird review food allergy therapies as part of an Annals pediatric series based upon the popular “7 for 11” sessions at the ACAAI annual scientific meeting. In the CME review this month, Dr. Idil Daloglu Ezhuthachan and colleagues evaluate outcomes more broadly in patients with food allergy and emphasize the need to harmonize outcome measures. In her editorial, Dr. Anna Nowak-Wegrzyn examines which outcomes matter in oral immunotherapy (OIT).
Several research articles focus on asthma. Dr. William A. McCann and colleagues evaluated whether an asthma risk questionnaire predicts both short- and long-term exacerbations, suggesting it may help optimize management. Regarding the definition of mild asthma, Dr. Emma Greimann and colleagues report survey findings showing differences between how specialists and generalists approach mild asthma, underscoring a need for further education on the definition and treatment of mild asthma. Zhenhao Xiao and colleagues provide an atlas of single-cell profiling to advance understanding of asthma and allergic rhinitis by examining both the upper and lower airways.
Other research articles include a study looking at OIT and the risk of eosinophilic esophagitis (EoE), with Dr. Timothy M. Buckey and colleagues finding similar low rates of EoE among patients undergoing either single- and multi-food OIT. Long-term efficacy and safety of donidalorsen for hereditary angioedema is also explored in this month’s research manuscripts. Finally, the popular ACAAI Yardstick series is back with an article by Dr. Andrew MacGinnitie and colleagues guiding treatment of pediatric hereditary angioedema.
As you read this issue of Annals, we hope you enjoy the start of the summer. As always, if you have comments, please consider sending correspondence to Annals (email: annals@ACAAI.org). We are always eager to hear how Annals has helped you improve the lives of your patients.
Jonathan Spergel, MD, PhD, FACAAI
Deputy Editor


