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Change to epinephrine coding

| July 7, 2025

Change to epinephrine coding

Beginning July 1, Medicare and other payers instituted a policy change that discontinues the code for billing epinephrine – J0171 – and replaced it with a set of codes that specify the manufacturer of the epinephrine. Note the reimbursement depends on the manufacturer, with generic epinephrine reimbursed at the lowest level. Epinephrine labeled as adrenalin has a separate J code.

Code Description Medicare Payment Limit
J0165 Injection, epinephrine, not otherwise specified, 0.1 mg 0.580
J0166 Injection, epinephrine (bpi), not therapeutically equivalent to j0165, 0.1 mg 2.282
J0167 Injection, epinephrine (hospira), not therapeutically equivalent to j0165, 0.1 mg 0.737
J0168 Injection, epinephrine (international medication systems), not therapeutically equivalent to j0165, 0.1 mg 2.176
J0169 Injection, epinephrine (adrenalin), not therapeutically equivalent to j0165, 0.1 mg 1.320

We suggest billing 96372 for the administration of the injection, and the appropriate J code above to cover the cost of the drug. If it is the patient’s drug, add one cent in the amount for the J code. However, if the practice is supplying the drug – as is usually the case with epinephrine –include the number of units used (as per the HCPCS table).

The Advocacy Council – ADVOCATING FOR ALLERGISTS AND THEIR PATIENTS.

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