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Learn about the intersection of allergies and autoimmunity and autoinflammatory diseases

| | July 13, 2026

Learn about the intersection of allergies and autoimmunity and autoinflammatory diseases

Summer is in full swing, and this month Annals of Allergy, Asthma & Immunology focuses on the intersection of allergies and autoimmunity and autoinflammatory diseases. The editorial from Jonathan Spergel, MD, PhD, FACAAI, says it all: “Allergy is more than type 2 disease.” The CME Review this month explores the overlap of allergy and autoimmune disease with inborn errors of immunity, and one of our reviews delves into the comorbidities of atopic dermatitis. While not directly linked to the theme, the other review in this issue examines neurologic mechanisms involved in cough — always a perplexing complaint. And this month there is a Master Clinician Series article exploring strategies to reduce needle anxiety in pediatric patients — just more evidence of how Annals provides information that is directly applicable to your clinic.

In terms of research articles this month, there are studies looking at vitamin D supplementation, as well as effects of biologics on corticosteroid use in asthma. Food allergy-related studies explore the relationship between sensitization to milk and cardiovascular outcomes, the natural history of fish-induced food protein-induced enterocolitis syndrome, and the impact of an allergist on food allergy anxiety. And, in case you were wondering if there are benefits to meeting with colleagues, an interesting study this month explores the benefits of getting together with your peers as a means to prevent burnout.

If you are in need of a little chuckle, be sure to check out the Marginal Zone this month. The tale of “The Mac Who Cried Wolf” reminds us of the role of macrophages in familial mediterranean fever (and also shows us how mad peritoneal epithelial cells look). Be sure to read the associated Cartootorial for more information. The author/illustrator of the Marginal Zone, Dr. Erin Reigh, also did the cover for this month’s issue, a DaVinci-like illustration.

As always, Annals strives to provide the most up-to-date and clinically relevant content, so that you can give your patients the cutting-edge care they deserve. Even as the impact of the journal increases (did you hear, our 2025 impact factor is now 7.1!), the editors strive to keep the articles focused on what clinicians want and need to read. Oh, and as we ask every month, if you have any thoughts about what we publish, please email Annals (annals@ACAAI.org) with any comments (good or bad) about articles and the utility of the journal.

Mitchell H. Grayson, MD, FACAAI
Editor-in-Chief

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