Influenza Vaccine Codes
As you prepare for the influenza season, we have the answers to coding for the 2025-26 influenza vaccine products. An administration code should always be reported in addition to the vaccine product code. Note: Third-party payers may have specific policies and guidelines that might require providing additional information on their claim forms.
Allergy/Immunology Coding Updates
HHS has released the 2026 ICD-10 updates, which become effective Oct. 1, 2025. Changes relevant to allergy/immunology are outlined below. Notable changes include:
- More specificity is required for anaphylactic reactions to milk, dairy products, and eggs.
- Changes to the language and rules of ICD-10 codes.
Note: All codes with an X in the 7th place require an
A (initial encounter), D (subsequent encounter), or
S (sequela) in the 7th position.
X in any other position is a placeholder for another number.
Most notable changes for allergists
S, T – Injury, poisoning and certain other consequences of external causes
Add: S30.86AX Insect bite (nonvenomous) of flank
Add: T36.AX5X Adverse effect of fluoroquinolone antibiotics
Delete: T78.07XX Anaphylactic reaction due to milk and dairy products
Add: T78.070X Anaphylactic reaction due to milk and dairy products with tolerance to baked milk
Add: T78.071X Anaphylactic reaction due to milk and dairy products with reactivity to baked milk
Add: T78.079X Anaphylactic reaction due to milk and dairy products, unspecified
Delete: T78.08XX Anaphylactic reaction due to eggs
Add: T78.080X Anaphylactic reaction due to egg with tolerance to baked egg
Add: T78.081X Anaphylactic reaction due to egg with reactivity to baked egg
Add: T78.089X Anaphylactic reaction due to eggs, unspecified
Delete: T78.1XXX Other adverse food reactions, not elsewhere classified
Add: T78.110X Other adverse food reactions due to milk and dairy products with tolerance to baked milk
Add: T78.111X Other adverse food reaction due to milk and dairy products with reactivity to baked milk
Add: T78.119X Other adverse food reaction due to milk and dairy products with baked milk tolerance/reactivity, unspecified
Add: T78.120X Other adverse food reaction due to egg with tolerance to baked egg
Add: T78.121X Other adverse food reaction due to egg with reactivity to baked egg
Add: T78.129X Other adverse food reaction due to egg with baked egg tolerance/reactivity, unspecified
Add: T78.19XX Other adverse food reactions, not elsewhere classified
Z – Factors influencing health status and contact with health services
Delete: Z59.86 Financial insecurity
Add: Z59.861 Financial insecurity, difficulty paying for utilities
Add: Z59.868 Other specified financial insecurity
Add: Z59.869 Financial insecurity, unspecified
Delete: Z91.011 Allergy to milk products
Add: Z91.0110 Allergy to milk products, unspecified
Add: Z91.0111 Allergy to milk products with tolerance to baked milk
Add: Z91.0112 Allergy to milk products with reactivity to baked milk
Delete: Z91.012 Allergy to eggs
Add: Z91.0120 Allergy to eggs, unspecified
Add: Z91.0121 Allergy to eggs with tolerance to baked egg
Add: Z91.0122 Allergy to eggs with reactivity to baked egg
Other changes:
D – Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Delete: D71 Functional disorders of polymorphonuclear neutrophils
Add: D711 Leukocyte adhesion deficiency
- LAD-I
- LAD-II
- LAD-III
- Leukocyte adhesion deficiency type I
- Leukocyte adhesion deficiency type II
- Leukocyte adhesion deficiency type III
Add: D718 Other functional disorders of polymorphonuclear neutrophils
- Cell membrane receptor complex [CR3] defect
- Chronic (childhood) granulomatous disease
- Congenital dysphagocytosis
- Progressive septic granulomatosis
Add: D719 Functional disorders of polymorphonuclear neutrophils, unspecified
Q – Congenital malformations, deformations, chromosomal abnormalities and genetic disorders
Delete: Q99.8 Other specified chromosome abnormalities
Add: Q99.89 Other specified chromosome abnormalities
R – Symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified
Delete: R76.8
Add: R76.81 Abnormal rheumatoid factor and anti-citrullinated protein antibody without rheumatoid arthritis
Add: R76.89 Other specified abnormal immunological findings in serum
We’ll monitor and continue to advise you on coding changes. We urge to review and consider how the new code changes may impact your practice and adjust accordingly. Be sure to check out our Coding Toolkit for more information on coding.
The Advocacy Council – ADVOCATING FOR ALLERGISTS AND THEIR PATIENTS.
