Omalizumab For Food Allergy – Part 1: Reviewing the Evidence

On February 16, 2024, the FDA announced the approval of the first biologic medication to treat patients with food allergy, omalizumab! In first part of a two-part series, we will review the evidence behind the Omalizumab as Monotherapy and as Adjunct Therapy to Multi-Allergen OIT in Food Allergic Children and Adults (OUtMATCH) study that led to this FDA indication. In Part 2, we will discuss important considerations in implementing omalizumab for food allergy in your practice.

Speakers:

• Robert Wood, MD, the Julie and Neil Reinhard Professor of Pediatric Allergy and Immunology and Division Director at Johns Hopkins University School of Medicine and Primary Investigator of the OUtMATCH study.
• Brian Vickery, MD, the Marcus Professor of Pediatric Immunology and Division Chief at Emory University and Children’s Healthcare of Atlanta. He was one of the site investigators of the OUtMATCH study.

Important Links:

Omalizumab for the Treatment of Multiple Food Allergies. N Engl J Med. 2024 Feb 25.
Robert A. Wood, MD; Alkis Togias, MD; Scott H. Sicherer, MD; Wayne G. Shreffler, MD, PhD; Edwin H. Kim, MD; Stacie M. Jones, MD; Donald Y.M. Leung, MD, PhD;  Brian P. Vickery, MD; J. Andrew Bird, MD;  Jonathan M. Spergel, MD; Ahmar Iqbal, MD, MBA; Julie Olsson, MD;  Monica Ligueros-Saylan, MD; Alkaz Uddin, PhD;  Agustin Calatroni, MS; Charmaine M.  Huckabee, MS; Nicole H. Rogers, BS; Nancy Yovetich, PhD; Jennifer Dantzer, MD; Kim Mudd, RN, MSN; Julie  Wang, MD; Marion Groetch, MS, RDN; David Pyle, MD, PhD; Corinne A. Keet, MD, PhD; Michael Kulis, PhD;  Sayantani B. Sindher, MD; Andrew Long, PhD; Amy M. Scurlock, MD;  Bruce J. Lanser, MD, MPH; Tricia Lee, MD;  Christopher Parrish, MD; Terri Brown-Whitehorn, MD; Amanda K. Rudman Spergel, MD; Maria Veri, PhD; Sanaz D. Hamrah, PharmD, MHSc; Erica Brittain, PhD; Julian Poyser, MPA, MS, FNP; Lisa M. Wheatley, MD, MPH; and R. Sharon Chinthrajah, MD.

Updated FDA label for omalizumab

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Today’s speakers have the following disclosures:

• Dr. Lee has nothing to disclose.
• Dr. Wood has consulted for Genentech.
• Dr. Vickery has consulted for Genentech and Novartis.