Spotlight on Annals

Phenotypes of diseases

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September 6, 2016

As the practice of medicine continues to mature in the 21st century, more and more clinical conditions which have classically been categorized as single diseases are now better described as syndromes or, in modern terms, phenotypes. Phenotypes can be designated based upon a variety of factors including overt or subtle differences in clinical presentations, diagnostic criteria, comorbidity risk and/or selection of therapeutic approaches with differences in response. The September issue of the Annals of Allergy, Asthma and Immunology addresses this with two articles in particular that describe phenotypes of diseases we have encountered for some time but have not had great success in therapy.

Allergy in the digital age: Social media and telemedicine

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May 30, 2016

The June issue of the Annals of Allergy, Asthma and Immunology, which will be online Tuesday, June 2, has many features for the practicing allergist-immunologist. Two interesting articles might seem to be a bit out of the “mainstream” offerings,   but I recommend them because of their high potential to be of use in your practice in the near future.

From penicillin allergy to dust mite sensitization

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March 28, 2016

The April issue of the Annals of Allergy, Asthma and Immunology is full of great features for the practicing allergist-immunologist. This month we present two articles which should have particular interest for our readers.

The first addresses the question of whether there might be a relationship between a history of penicillin allergy and the presence of chronic urticaria. Silverman and colleagues performed a retrospective review of over 11,000 medical records to find that the prevalence of self-reported penicillin allergy in urticaria patients was three times that of the general population and the prevalence of urticaria was also three time higher in patients with self-reported penicillin allergy than patients who did not report a penicillin allergy. The authors suggest that an inquiry about penicillin allergy should accompany the workup for chronic urticaria.

Happy anniversary, IgE!

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February 22, 2016

The March issue of Annals of Allergy, Asthma and Immunology focuses on issues and findings associated with IgE. As you likely know, 2016 is the 50th anniversary of the discovery of IgE. Two articles help to focus the March issue on what IgE is and what it can do.

In an elegant perspective article, Tom Platts-Mills and colleagues provide a succinct review of the history of IgE – how it was discovered, who was involved and some of the interesting pitfalls and opportunities that shaped the discovery pathway. They then track the development of assay for total and specific IgE that we all use in our routine clinical practices and outline the events due to the expertise and good fortune of the researchers involved.

Disease management is a partnership

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November 23, 2015

As the world of organized medicine continues to evolve, we as practicing allergists-immunologists are affected by the need to be more efficient and accurate in our diagnostic and therapeutic acumen as well as remembering that disease management is a partnership between us/our staff and the patient/family. In the December issue of the Annals of Allergy, Asthma and Immunology, two articles in particular highlight these issues.